single cell sequencing

Single-cell DNA methylation in the human brain

The human brain is a complex organ with a wide variety of cell types and intricate gene regulation processes. Epigenetic modifications, such as DNA methylation, play a crucial role in gene expression and regulation. Studying DNA methylation patterns at a single-cell resolution can provide insights into the diverse cellular composition and functional diversity of the human brain. Prof. Joseph R. Ecker from the Salk Institute for Biological Studies has recently reported the discovery concerning DNA methylation in brain maps.